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Antibacterial Effect and Proposed Mechanism of Action of a Topical Surgical Adhesive

Published In: American Journal of Infection Control

Medical adhesives effectively hold closed approximated skin edges of wounds from surgical incisions, including punctures from minimally invasive surgery. In addition, they have been reported to be antibacterial against gram-positive bacteria.

Using membrane filtration to capture all organisms after contact with 2-octyl cyanoacrylate product for 3 minutes, we quantified the number of survivors. Controls were performed to rule out that the noted level of kill was caused by carryover product in the test system.

Authors: Daniel Prince, PhD; Zankhna Solanki, MS; Remy Varughese, BS; Jozef Mastej, BS; Derek Prince, MS


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