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Disinfectant-Efficacy Testing – Coupon/Carrier Method

Published Date: March 4, 2022

Disinfectants must be qualified on the surfaces in a pharmacopeial-manufacturing environment prior to their use in the facility. Building a study with robust parameters and avoiding common pitfalls are critical to avoid negative responses from regulatory agencies. Spending more time on study design and development upfront will save valuable resources in the long run.

The presenters (learn more about them below) attempt to bridge the gap between laboratory conditions and environmental conditions. Test-method acceptance criteria and interpretation of coupon study results are also discussed. This webinar provides insight into how the results of a coupon study can be utilized to improve cleaning procedures.

The following important points are discussed:

  • Study Design: How to choose parameters that are representative of your facility while meeting regulatory expectations.
  • Indications that initial or subsequent disinfectant-efficacy testing needs to be performed.
  • Interpretation of results: Translating microorganism log reductions into useful information on the efficacy of facility cleaning procedures and disinfectants.

The goal of this webinar is to provide a general overview of disinfectant-efficacy testing and to provide a detailed methodology to assist in designing coupon studies that accurately represent facility procedures.


Aaron Zahne

Study Director, Antimicrobials and Filtration

Prior to working at Nelson Labs, Aaron worked in the raw-dairy industry, where he focused on antibiotic detection and bacterial growth. Since joining Nelson, Aaron has directed cleanroom-disinfection validations and antimicrobial-effectiveness studies that meet the industry standard. Aaron holds a bachelor's degree in microbiology and molecular biology from the University of Wyoming.


Adam Staples

Study Director, Antimicrobials and Filtration

Adam has worked for Nelson Labs for nearly 10 years. He has worked in the Sterility Assurance group as a testing analyst and a study director. He is currently working in the antimicrobials and filtration section, overseeing kill time, microbial growth, tissue log reduction, and disinfection validations. He received his Bachelor of Science degree in microbiology from Weber State University.

Complete the form below to access the webinar.