Header Artwork
Header Artwork



Calling Attention to Burkholderia spp. and Mitigating Risk Through a Robust Preservative System

Published Date: March 15, 2022

Controlling the growth of microbes within non-sterile formulations is critical to meet regulatory expectations and to provide a safe and effective product.

Rising concerns over persistent opportunistic pathogens is calling attention to the Burkholderia cepacia complex (Bcc). The Bcc has proven to be a significant health risk to patients who are immunocompromised, relying on ventilators, or suffering from underlying illnesses.  This Gram-negative, rod-shaped bacterium is an opportunistic pathogen that can establish itself in water systems and surfaces of manufacturing equipment.

Assuring an effective preservative system for Burkholderia spp. is not just for drug manufactures; it is also for cosmetics and personal-care products. The FDA has issued several product recalls that have included oral liquid drugs, liquid dietary supplements, saline solutions, and hand sanitizers, which were all associated with persistent opportunistic pathogens.

In this webinar the presenter, Aaron Zahne, provides a general overview of the antimicrobial-preservative-effectiveness test and its use to mitigate risk. He also addresses questions related to the preservative system’s effectiveness on other opportunistic organisms of concern.

Watch this webinar to learn the following, among other things:

  • Study design
  • Importance of suitability testing
  • Interpreting the results

This webinar offers considerations for both the pharmaceutical and personal-care industries.


Aaron Zahne

Study Director, Antimicrobials and Filtration

Prior to working at Nelson Labs, Aaron worked in the raw-dairy industry, where he focused on antibiotic detection and bacterial growth. Since joining Nelson, Aaron has directed cleanroom-disinfection validations and antimicrobial-effectiveness studies that meet the industry standard. Aaron holds a bachelor's degree in microbiology and molecular biology from the University of Wyoming.

Complete the form below to access the webinar.