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PTT Test

PTT Test

The Partial Thromboplastin Time (PTT) test is a general screening test for the detection of coagulation abnormalities in the intrinsic pathway. This test is performed on devices/materials that have direct contact with circulating blood.

Download the biocompatibility test matrix. [Based on ISO 10993-1:2010 (E) and FDA G95-1 Guidelines]

Applicable Standards

ANSI/AAMI/ISO 10993-4    |    ANSI/AAMI/ISO 10993-12

Pricing/Quote

Test Price Request Quote
HCX220 - Hemocompatibility: Partial Thromboplastin Time (PTT), Human plasma
Per test1+$555.00
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HCX225 - Hemocompatibility: Partial Thromboplastin Time (PTT), Human plasma, test & predicate
Per test1+$1,060.00
Add
HCX220 - Hemocompatibility: Partial Thromboplastin Time (PTT), Human plasma
Per test1+$555.00
HCX225 - Hemocompatibility: Partial Thromboplastin Time (PTT), Human plasma, test & predicate
Per test1+$1,060.00

Turn Around Time

Standard turn around times (TAT) are listed below. Ask an expert for a specific consultation on your product.

Code Test TAT
HCX220 Hemocompatibility: Partial Thromboplastin Time (PTT), Human plasma 14
HCX225 Hemocompatibility: Partial Thromboplastin Time (PTT), Human plasma, test & predicate 14
Code TAT
HCX220 14
HCX225 14

Sample Specifications

HCX220: 1 device or 12-24 cm2
HCX225: 1 device or 12-24 cm2 each (test article & predicate)

Study Outline

The Partial Thromboplastin Time (PTT) assay was developed from the plasma recalcification and uses a PTT reagent as a platelet substitute. The sample is exposed to citrated plasma for 60 minutes at a validated temperature. The exposed plasma is divided into six replicates and incubated at 37 ± 1°C for 3 minutes.

The PTT reagent is then added followed by the addition of a calcium chloride solution which inactivates the anticoagulant and allows a clot to form. The amount of time elapsed prior to the clot formation is monitored and recorded. Evaluation of the clotting times is performed using statistical comparisons to the controls.