Version: 1.1.5037.23448-7fe1cda529b97ebc52da0f2bbefb0d41deb9638a

Item was added to the Sample Submission form

Item was added to the Quote Request form

Differential Scanning Calorimetry

Differential Scanning Calorimetry

The Differential Scanning Calorimetry (DSC) test determines thermodynamic events such as melting point, glass transition temperatures, crystallization temperatures and other phase changes. This test is performed on polymers and liquids. It is used for material characterization, lot to lot comparisons and sample purity.

Testing meets the criteria set forth in USP General Chapter 32 and the National Formulary 27, 891. Nelson Laboratories offers fast, accurate and dependable DSC testing services.

Applicable Standards

  • ISO 10993-12
  • ISO 10993-18

Test Options

Standard turn around times (TAT) are listed below. Ask an expert for a specific consultation on your product.

Code Test TAT (days) Request Quote
DSC101 Differential Scanning Calorimetry (DSC) w/ sample preparation 10 Add
DSC105 Differential Scanning Calorimetry (DSC), repeat scan w/ thermal cycle, each Add
DSC101 - Differential Scanning Calorimetry (DSC) w/ sample preparation
10 days
DSC105 - Differential Scanning Calorimetry (DSC), repeat scan w/ thermal cycle, each
Standard TAT not available for this product

Sample Specifications

DSC101: 5-20 mg

Study Outline

The Differential Scanning Calorimetry (DSC) test uses a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference are measured as a function of temperature. Both the sample and reference are maintained at nearly the same temperature throughout the experiment. The operational range of our instrument is ambient to 500°C.

Generally, the temperature program for a DSC analysis is designed such that the sample holder temperature increases linearly as a function of time. The reference sample should have a well-defined heat capacity over the range of temperatures to be scanned.

The main application of DSC is in studying phase transitions, such as melting, glass transitions, crystallizations and exothermic decompositions, with each of their temperatures and energies. These transitions involve energy changes or heat capacity changes that can be detected by DSC with great sensitivity.