Sub-acute/sub-chronic toxicity
Subacute and Subchronic Toxicity determines the systemic effect of repeated doses of materials or their extracts for no less than 24 hours and no greater than 10% of the total life span of the test animal. The test substance or extract is administered to the animal for 14 days, and is observed each day for signs of toxicity: weight change, appetite, signs of disease or abnormal behavior. Then, the effects are evaluated and a histopathology is conducted on all animals. This is outlined in ISO 10993-11.
Optional Tests for Sub-acute/sub-chronic toxicity
Sub-Acute toxicity with Histopathology ISO 10993
Sub-chronic toxicity with histopathology ISO 10993
